MOLECULAR NUGGETS

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The Great Transformation: Cracking the Code of Life

Fri, Apr 24th, 2026 8:05 am

April 25th is DNA Day which celebrates the discovery of the structure of DNA and the publication of the first draft of the Human genome.  It is hard to imagine now, however less than 100 years ago, we did not know that DNA was responsible for the transmission of genetic information.  While all the biomolecules had been identified and the principle of the gene was understood, the physical properties were completely unknown.  A series of what I think are some of the most elegant studies from the late 1920’s into the 1940’s led to the understanding that DNA was the genetic material.

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Cracking the Code of Life

TB Then & Now: Koch’s Discovery Meets Modern Diagnostics

TB Then & Now: Koch’s Discovery Meets Modern Diagnostics

Mar 24th, 2026

Observed each year on March 24, World TB Day raises awareness of the ongoing global tuberculosis epidemic and commemorates Robert Koch’s 1882 discovery of Mycobacterium tuberculosis, the bacterium responsible for the disease. Tuberculosis has...

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Zombosomes: The “Undead” Vesicles Spreading Parkinson’s Pathology

Zombosomes: The “Undead” Vesicles Spreading Parkinson’s Pathology

Feb 27th, 2026

Cells are very dynamic creatures. We typically think about them in the context of growing, dividing, and specializing to generate organisms. The orchestra of activities to allow animals to thrive is almost inconceivable. They are also very sensitive...

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Cuckoos: Masters of Nest Deception

Nov 21st, 2025

Nature's most notorious deadbeat parents just got more interesting. Common cuckoos don't build nests or raise their young. Instead, they sneak their eggs into other birds' nests, tricking unsuspecting foster parents into doing all the work, a...

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Cancer's Hidden Circle

Cancer’s Hidden Circles: How Extra DNA Helps Tumors Survive

Oct 17th, 2025

It seems like cancer cells are always one step ahead of us. In many cases whatever we throw at them, they can adapt and survive.  Don’t get me wrong, we have made tremendous progress in targeting specific cancer cells and holding the disease at...

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Cell Division Secrets

Cell Division Secrets: The Tiny Tug-of-War Inside You

Sep 17th, 2025

When cells divide, they must ensure that each daughter cell receives an identical set of chromosomes. To achieve this, each chromosome is first duplicated, forming two identical sister chromatids that are connected at a central point called the...

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Molecular Nuggets

Genes That Rise Like Dough

Aug 21st, 2025

When we think of genome evolution, we typically think of the accumulation of mutations and variants within a gene that renders its function to be improved or altered and allows the individual to be better adapted to the environment and more likely...

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