is an external quality control
used to monitor the analytical performance of the extraction,
amplification and detection of test systems used in the
qualitative measurement of the Factor II (Prothrombin) and Factor
V genes for mutations Factor II G20210A and Factor V
Leiden, respectively.
Each bottle of TRC Genotype Control contains two
synthetic alleles of Factor II DNA and two synthetic alleles of
Factor V DNA suspended in a non-infectious, blood-like matrix.
Each allele contains a segment of the Factor II gene or a segment
of the Factor V gene. Alleles carry either a mutation (Factor
II G20210A or Factor V Leiden (G1691A)), or wild type
DNA. All alleles have been quality scored sequenced in entirety.
Analysis of TRC Genotype Control provides the laboratory
with valuable experience by demonstrating test results of rare
genotypes.
The alleles have been carefully mixed to produce three bottles
containing three different genotypes: homozygous wild type
(WT/WT), heterozygous (G20210A / WT and G1691A /
WT), and homozygous mutant (G20210A / G20210A and G1691A/
G1691A).
INTROL™ is provided for
Research Use Only.
MSDS
